C-reactive protein genetic variant is associated with diabetic retinopathy in Chinese patients with type 2 diabetes
نویسندگان
چکیده
منابع مشابه
C-reactive protein genetic variant is associated with diabetic retinopathy in Chinese patients with type 2 diabetes
BACKGROUND Diabetic retinopathy (DR) is an important microvascular complication of diabetes with a high concordance rate in patients with diabetes. Inflammation is supposed to participate in the development of DR. This study aimed to investigate whether genetic variants of CRP are associated with DR. METHODS A total of 1,018 patients with type 2 diabetes were recruited in this study. Of these...
متن کاملCPVL/CHN2 Genetic Variant Is Associated With Diabetic Retinopathy in Chinese Type 2 Diabetic Patients
OBJECTIVE Diabetic nephropathy and retinopathy are two important microvascular diabetes complications with a high concordance rate in diabetic patients. A recent genome-wide association study in type 1 diabetic patients of European descent identified four loci to be associated with diabetic nephropathy. The aim of this study was to test the effects of single nucleotide polymorphisms (SNPs) from...
متن کاملFactors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus
Objective. To investigate the risk factors of DR in Chinese T2DM patients. Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the relation between DR and clinical variables. Logistic regression models were used to assess risk for t...
متن کاملEvaluation of Plasma Protein Oxidation Biomarkers in type 2 Diabetic Patients with Retinopathy
Objective: Retinopathy is a microvascular complication of diabetes and leading cause of blindness throughout the world. The proteins as the most chemical substances in the cells are exposed to oxidative damages of free radicals. The aim of this study was to evaluate the values of protein oxidation biomarkers in diabetic patients with retinopathy. Materials and Methods: This study was done on 3...
متن کاملInsulin resistance in Chinese patients with type 2 diabetes is associated with C-reactive protein independent of abdominal obesity
BACKGROUND There is debate as to whether the association between C-reactive protein (CRP) and insulin resistance is independent of body fatness, particularly central obesity. Therefore, the association among CRP, insulin resistance and obesity was analyzed in Chinese patients with type 2 diabetes. METHODS The study included 520 Chinese patients diagnosed with type 2 diabetes with CRP levels n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Endocrine Disorders
سال: 2015
ISSN: 1472-6823
DOI: 10.1186/s12902-015-0006-5